Anti-Sam68/KHDRBS1 Antibody Picoband®

SKU: A01717-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Immunofluorescence, 5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human, Mouse
ELISA, 0.1-0.5 μg/ml, -

Gene Name: KHDRBS1

Specificity:

Background: KH domain-containing, RNA-binding, signal transduction-associated protein 1 is a protein that in humans is encoded by the KHDRBS1 gene. This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants.

Immunogen: E.coli-derived human Sam68/KHDRBS1 recombinant protein (Position: M21-E239).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Barlat, I., Maurier, F., Duchesne, M., Guitard, E., Tocque, B., Schweighoffer, F. A role for Sam68 in cell cycle progression antagonized by a spliced variant within the KH domain. J. Biol. Chem. 272: 3129-3132, 1997. 2. Bianchi, E., Barbagallo, F., Valeri, C., Geremia, R., Salustri, A., De Felici, M., Sette, C. Ablation of the Sam68 gene impairs female fertility and gonadotropin-dependent follicle development. Hum. Molec. Genet. 19: 4886-4894, 2010. 3. Carlosama, C., Patino, L. C., Beau, I., Morel, A., Delemer, B., Young, J., Binart, N., Laissue, P. A novel mutation in KHDRBS1 in a patient affected by primary ovarian insufficiency. (Letter) Clin. Endocr. 89: 245-246, 2018.

Uniprot ID: Q07666

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 68 kDa

Calculated Molecular Weight: 54405 MW

Gene ID: 10657

Protein Name: KH domain-containing, RNA-binding, signal transduction-associated protein 1

Gene Full Name: KH RNA binding domain containing, signal transduction associated 1

Synonyms: KHDRBS1; p62; p68; Sam68