Anti-Relaxin 1/RLN1 Antibody Picoband®

SKU: A08367-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Rat

Applications: IHC,WB

Application Details: Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml

Gene Name: RLN1

Specificity: No cross reactivity with other proteins.

Background: Relaxin 1 is a member of relaxin-like peptide family. Relaxin gene maps to human chromosome 19 near D19Mit23. Relaxin is a peptide hormone produced by the corpora lutea of ovaries during pregnancy in many mammalian species, including man. Relaxin widens the pubic bone and facilitates labor, it also softens the cervix (cervical ripening), and relaxes the uterine musculature. However, its significance may reach much further. Relaxin affects collagen metabolism, inhibiting collagen synthesis and enhancing its breakdown by increasing matrix metalloproteinases. It also enhances angiogenesis and is a potent renal vasodilator.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Relaxin 1, which shares 45.2% amino acid (aa) sequence identity with mouse Relaxin 1.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Hsu, S. Y., Nakabayashi, K., Nishi, S., Kumagai, J., Kudo, M., Sherwood, O. D., Hsueh, A. J. W. Activation of orphan receptors by the hormone relaxin. Science 295: 671-674, 2002. 2. Schwabe, C., Bullesbach, E. E. Relaxin: structures, functions, promises, and nonevolution. FASEB J. 8: 1152-1160, 1994.

Uniprot ID: P04808

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 21 kDa

Calculated Molecular Weight:

Gene ID: 6013

Protein Name: Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

Gene Full Name: relaxin 1

Synonyms: relaxin 1; H1; H1RLX; RLXH1; bA12D24.3.1; bA12D24.3.2; RLN1