Anti-RBMS3 Antibody Picoband®

SKU: A12416-3

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,IF,IHC,ICC,WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2μg/ml, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: RBMS3

Specificity: No cross reactivity with other proteins.

Background: RNA-binding motif, single-stranded-interacting protein 3 is a protein that in humans is encoded by the RBMS3 gene. It is mapped to 3p24.1. This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2 (I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human RBMS3 recombinant protein (Position: T350-P437).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Penkov, D., Ni, R., Else, C., Pinol-Roma, S., Ramirez, F., Tanaka, S. Cloning of a human gene closely related to the genes coding for the c-myc single-strand binding proteins. Gene 243: 27-36, 2000. 2. Kanaoka, Y., Nojima, H. SCR: novel human suppressors of cdc2/cdc13 mutants of Schizosaccharomyces pombe harbour motifs for RNA binding proteins. Nucleic Acids Res. 22: 2687-2693, 1994. 3. Negishi, Y., Nishita, Y., Saegusa, Y., Kakizaki, I., Galli, I., Kihara, F., Tamai, K., Miyajima, N., Iguchi-Ariga, S. M. M., Ariga, H. Identification and cDNA cloning of single-stranded DNA binding proteins that interact with the region upstream of the human c-myc gene. Oncogene 9: 1133-1143, 1994.

Uniprot ID: Q6XE24

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 55 kDa

Calculated Molecular Weight:

Gene ID: 27303

Protein Name: RNA-binding motif, single-stranded-interacting protein 3

Gene Full Name: RNA binding motif single stranded interacting protein 3

Synonyms: RNA binding motif single stranded interacting protein 3; RBMS3