Anti-RAB43 Antibody Picoband®

SKU: A09315-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RAB43

Specificity:

Background: Ras-related GTP-binding protein 43 (RAB43) is a member ofthe Rassuperfamily. RAB43 is mainly located in endoplasmic reticulum and Golgi, and plays a role as a key regulator of vesicle movement,signal transduction and tethering membrane eventsin membrane trafficking.

Immunogen: E.coli-derived human RAB43 recombinant protein (Position: Q14-E206).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Jiang, Y. , Sun, Y. , Hu, J. , Yu, N. , & Xu, H. . (2019). A germline mutation in rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome. BMC Cancer, 19(1). 2. ChunmanLi, ZheWei, YiFan, WeiHuang, YunchaoSu, & HonglinLi, et al. (2017). The gtpase rab43 controls the anterograde er-golgi trafficking and sorting of gpcrs. Cell Reports. 3. Ming-Zhi, Han, Bin, Huang, An-Jing, & Chen, et al. (2017). High expression of rab43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas. Oncology reports.

Uniprot ID: Q86YS6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 23 kDa

Calculated Molecular Weight:

Gene ID: 339122

Protein Name: Ras-related protein Rab-43

Gene Full Name: RAB43, member RAS oncogene family

Synonyms: ISY1; RAB41; RAB43; Ras related protein Rab 41; Ras related protein Rab 43