Anti-RAB39A/B Antibody Picoband®

SKU: A11551-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RAB39A/B

Specificity:

Background: This gene encodes a protein which is a member of the Rab family.The Rab family of proteins is a member of the Ras superfamily of monomeric G proteins. Approximately 70 types of Rabs have now been identified in humans. Rab GTPases regulate many steps of membrane traffic, including vesicle formation, vesicle movement along actin and tubulin networks, and membrane fusion. These processes make up the route through which cell surface proteins are trafficked from the Golgi to the plasma membrane and are recycled. Surface protein recycling returns proteins to the surface whose function involves carrying another protein or substance inside the cell, such as the transferrin receptor, or serves as a means of regulating the number of a certain type of protein molecules on the surface.

Immunogen: E.coli-derived human RAB39A/B recombinant protein (Position: M1-C217).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Becker, C. E., Creagh, E. M., O'Neill, L. A. J. Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1-beta secretion. J. Biol. Chem. 284: 34531-34537, 2009. Note: Erratum: J. Biol. Chem. 291: 24800 only, 2016. 2. Cruz, F. M., Colbert, J. D., Rock, K. L. The GTPase Rab39a promotes phagosome maturation into MHC-I antigen-presenting compartments. EMBO J. 39: e102020, 2020. 3. Gross, M. B. Personal Communication. Baltimore, Md. 10/1/2021.

Uniprot ID: Q14964/Q96DA2

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 20-24 kDa

Calculated Molecular Weight:

Gene ID: 54734/116442

Protein Name: Signal transducer and activator of transcription

Gene Full Name: RAB39A/B, member RAS oncogene family

Synonyms: Rab 39; RAB39; RAB39A; Ras related protein Rab 39A; RAB39B; Ras related protein Rab 39B