Anti-RAB34 Antibody Picoband®

SKU: A11097-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: RAB34

Specificity:

Background: Ras-related protein Rab-34 is a protein that in humans is encoded by the RAB34 gene. This gene encodes a protein belonging to the RAB family of proteins, which are small GTPases involved in protein transport. This family member is a Golgi-bound member of the secretory pathway that is involved in the repositioning of lysosomes and the activation of macropinocytosis. Alternative splicing of this gene results in multiple transcript variants. An alternatively spliced transcript variant produces the nine-amino acid residue-repeats (NARR) protein, which is a functionally distinct nucleolar protein resulting from a different reading frame.

Immunogen: E.coli-derived human RAB34 recombinant protein (Position: M1-P259).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Chen, T., Han, Y., Yang, M., Zhang, W., Li, N., Wan, T., Guo, J., Cao, X. Rab39, a novel Golgi-associated Rab GTPase from human dendritic cells involved in cellular endocytosis. Biochem. Biophys. Res. Commun. 303: 1114-1120, 2003. 2. Speight, P., Silverman, M. Diacylglycerol-activated Hmunc13 serves as an effector of the GTPase Rab34. Traffic 6: 858-865, 2005. 3. Sun, P., Yamamoto, H., Suetsugu, S., Miki, H., Takenawa, T., Endo, T. Small GTPase Rah/Rab34 is associated with membrane ruffles and macropinosomes and promotes macropinosome formation. J. Biol. Chem. 278: 4063-4071, 2003.

Uniprot ID: Q9BZG1

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 29 kDa

Calculated Molecular Weight: 29,044 MW

Gene ID: 83871

Protein Name: Ras-related protein Rab-34

Gene Full Name: RAB34, member RAS oncogene family

Synonyms: RAB34; RAB39; RAH; Ras related protein Rab 34; Ras related protein Rab 39; Ras related protein Rah