Anti-PTGES2/Gbf1 Antibody Picoband®

SKU: A06706-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,IF,IHC,ICC,WB,Flow Cytometry

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PTGES2

Specificity:

Background: Microsomal prostaglandin E synthase-2 (mPGES-2) or Prostaglandin E synthase 2 is an enzyme that in humans encoded by the PTGES2 gene located on chromosome 9. The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene.

Immunogen: E.coli-derived human PTGES2/Gbf1 recombinant protein (Position: L100-I370).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Hu, J., Meng, Q., Roy, S. K., Raha, A., Hu, J., Zhang, J., Hashimoto, K., Kalvakolanu, D. V. A novel transactivating factor that regulates interferon-gamma-dependent gene expression. J. Biol. Chem. 277: 30253-30263, 2002. 2. Nitz, I., Fisher, E., Grallert, H., Li, Y., Gieger, C., Rubin, D., Boeing, H., Spranger, J., Lindner, I., Schreiber, S., Rathmann, W., Gohlke, H., Doring, A., Wichmann, H.-E., Schrezenmeir, J., Doring, F., Illig, T. Association of prostaglandin E synthase 2 (PTGES2) arg298-to-his polymorphism with type 2 diabetes in two German study populations. J. Clin. Endocr. Metab. 92: 3183-3188, 2007. 3. Tanikawa, N., Ohmiya, Y., Ohkubo, H., Hashimoto, K., Kangawa, K., Kojima, M., Ito, S., Watanabe, K. Identification and characterization of a novel type of membrane-associated prostaglandin E synthase. Biochem. Biophys. Res. Commun. 291: 884-889, 2002.

Uniprot ID: Q9H7Z7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 42 kDa

Calculated Molecular Weight: 104553 MW

Gene ID: 80142

Protein Name: Prostaglandin E synthase 2

Gene Full Name: prostaglandin E synthase 2

Synonyms: C9orf15; GBF1; mPGES 2; PGES2; prostaglandin E synthase 2; PTGES2