Anti-Polymeric immunoglobulin receptor/PIGR Picoband® Antibody

SKU: A01624

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: ELISA,Flow Cytometry,WB

Application Details: Western blot, 0.25-0.5μg/ml, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Rat
ELISA, 0.1-0.5μg/ml, -

Gene Name: Pigr

Specificity: No cross reactivity with other proteins.

Background: Polymeric immunoglobulin receptor (pIgR) is a transmembrane protein that in humans is encoded by the PIGR gene. It is mapped to 1 E4; 1 56.89 cM. This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.

Immunogen: E.coli-derived mouse Polymeric immunoglobulin receptor/PIGR recombinant protein (Position: D34-A771).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Davidson, M. K., Le Beau, M. M., Eddy, R. L., Shows, T. B., DiPietro, L. A., Kingzette, M., Hanly, W. C. Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31-q41. Cytogenet. Cell Genet. 48: 107-111, 1988. 2. Hood, L., Kronenberg, M., Hunkapiller, T. T cell antigen receptors and the immunoglobulin supergene family. Cell 40: 225-229, 1985. 3. Krajci, P., Gedde-Dahl, T., Jr., Hoyheim, B., Rogde, S., Olaisen, B., Brandtzaeg, P. The gene encoding human transmembrane secretory component (locus PIGR) is linked to D1S58 on chromosome 1. Hum. Genet. 90: 215-219, 1992.

Uniprot ID: O70570

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 85-100 kDa

Calculated Molecular Weight:

Gene ID: 18703

Protein Name: Polymeric immunoglobulin receptor

Gene Full Name: polymeric immunoglobulin receptor

Synonyms: polymeric immunoglobulin receptor; PIGR; Poly Ig receptor