Anti-Plunc/BPIFA1 Antibody Picoband®

SKU: A03162-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse
ELISA, 0.1-0.5 μg/ml, -

Gene Name: BPIFA1

Specificity:

Background: Palate, lung, and nasal epithelium clone protein[5] (PLUNC) is a gene encoding a secretory protein. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in the upper airways and may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only three are known.

Immunogen: E.coli-derived human Plunc/BPIFA1 recombinant protein (Position: L64-V256).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Bingle, C. D., Bingle, L. Characterisation of the human plunc gene, a gene product with an upper airways and nasopharyngeal restricted expression pattern. Biochim. Biophys. Acta 1493: 363-367, 2000. 2. Bingle, C. D., Craven, C. J. PLUNC: A novel family of candidate host defence proteins expressed in the upper airways and nasopharynx. Hum. Molec. Genet. 11: 937-943, 2002. 3. Chu, H. W., Thaikoottathil, J., Rino, J. G., Zhang, G., Wu, Q., Moss, T., Refaeli, Y., Bowler, R., Wenzel, S. E., Chen, Z., Zdunek, J., Breed, R., Young, R., Allaire, E., Martin, R. J. Function and regulation of SPLUNC1 protein in mycoplasma infection and allergic inflammation. J. Immun. 179: 3995-4002, 2007.

Uniprot ID: Q9NP55

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 27 kDa

Calculated Molecular Weight: 65411 MW

Gene ID: 51297

Protein Name: BPI fold-containing family A member 1

Gene Full Name: BPI fold containing family A member 1

Synonyms: BPIFA1; LPLUNC3; Lung specific protein X; LUNX; NASG; PLUNC; Protein Plunc; SPLUNC1; SPURT; Von Ebner protein Hl