Anti-PLCB1 Antibody Picoband®

SKU: A02817-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: PLCB1

Specificity:

Background: PLCB1 is also known as PLC-I, EIEE12 or PLC154. The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human PLCB1 recombinant protein (Position: H9-D834). Human PLCB1 shares 98.8% and 98.5% amino acid (aa) sequence identity with mouse and rat PLCB1, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Guo Y, et al. A loss in cellular protein partners promotes α-synuclein aggregation in cells resulting from oxidative stress. Biochemistry, 2013 Jun 4. 2. Ngoh A, et al. Severe infantile epileptic encephalopathy due to mutations in PLCB1: expansion of the genotypic and phenotypic disease spectrum. Dev Med Child Neurol, 2014 Nov. 3. Philip F, et al. Role of phospholipase C-β in RNA interference. Adv Biol Regul, 2013 Sep.

Uniprot ID: Q9NQ66

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 150 kDa

Calculated Molecular Weight:

Gene ID: 23236

Protein Name: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Gene Full Name: phospholipase C beta 1

Synonyms: phospholipase C beta 1; DEE12; EIEE12; PI-PLC; PLC-154; PLC-I; PLC-beta-1; PLC154A; PLCB1B; PLCB1; KIAA0581; Phospholipase C I; PI PLC; PLC 154; PLC beta 1; PLC I; PLC154; PLCB1