Anti-ODC1 Antibody Picoband®

SKU: A03138-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ODC1

Specificity:

Background: This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

Immunogen: E.coli-derived human ODC1 recombinant protein (Position: M1-H450). Human ODC1 shares 90.9% and 91.6% amino acid (aa) sequence identity with mouse and rat ODC1, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Alhonen-Hongisto, L., Leinonen, P., Sinervirta, R., Laine, R., Winqvist, R., Alitalo, K., Janne, O. A., Janne, J. Mouse and human ornithine decarboxylase genes: methylation polymorphism and amplification. Biochem. J. 242: 205-210, 1987. 2. Brabant, M., McConlogue, L., van Daalen Wetters, T., Coffino, P. Mouse ornithine decarboxylase gene: cloning, structure, and expression. Proc. Nat. Acad. Sci. 85: 2200-2204, 1988. 3. Bupp, C. P., Schultz, C. R., Uhl, K. L., Rajasekaran, S., Bachmann, A. S. Novel de novo pathogenic variant in the ODC1 gene in a girl with developmental delay, alopecia, and dysmorphic features. Am. J. Med. Genet. 176A: 2548-2553, 2018.

Uniprot ID: P11926

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 51 kDa

Calculated Molecular Weight: 51,55 kDa

Gene ID: 4953

Protein Name: Ornithine decarboxylase

Gene Full Name: ornithine decarboxylase 1

Synonyms: ODC; ODC1; Ornithine decarboxylase; ornithine decarboxylase 1