Anti-NFATC4 Antibody Picoband®

SKU: A02599-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,Flow Cytometry,IHC,ICC,WB

Application Details: Western blot, 0.1-0.5μg/ml
Immunohistochemistry (Frozen Section), 0.5-1μg/ml
Immunocytochemistry, 0.5-1μg/ml
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells
ELISA, 0.1-0.5μg/ml

Gene Name: NFATC4

Specificity: No cross reactivity with other proteins.

Background: Nuclear factor of activated T-cells, cytoplasmic 4 is a protein that in humans is encoded by the NFATC4 gene. This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4.

Immunogen: E. coli-derived human NFATC4 recombinant protein (Position: Q413-D522).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Hoey T, Sun YL, Williamson K, Xu X (May 1995). Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity. 2 (5): 461–72. 2. Yang T, Davis RJ, Chow CW (Oct 2001). Requirement of two NFATc4 transactivation domains for CBP potentiation. The Journal of Biological Chemistry. 276 (43): 39569–76.

Uniprot ID: Q14934

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 95120 kDa

Calculated Molecular Weight:

Gene ID: 4776

Protein Name: Nuclear factor of activated T-cells, cytoplasmic 4

Gene Full Name: nuclear factor of activated T cells 4

Synonyms: NF AT3; NF ATc4; NFAT3; NFATC4; NF-AT3; NF-ATC4