Anti-NEUROD2 Antibody Picoband®

SKU: A07904-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: NEUROD2

Specificity:

Background: Neurogenic differentiation factor 2 is a protein that in humans is encoded by the NEUROD2 gene. This gene encodes a member of the neuroD family of neurogenic basic helix-loop-helix (bHLH) proteins. Expression of this gene can induce transcription from neuron-specific promoters, such as the GAP-43 promoter, which contain a specific DNA sequence known as an E-box. The product of the human gene can induce neurogenic differentiation in non-neuronal cells in Xenopus embryos, and is thought to play a role in the determination and maintenance of neuronal cell fates.

Immunogen: E.coli-derived human IDI2 recombinant protein (Position: M1-V227). Human IDI2 shares 68.2% and 62.6% amino acid (aa) sequence identity with mouse and rat IDI2, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Ince-Dunn, G., Hall, B. J., Hu, S.-C., Ripley, B., Huganir, R. L., Olson, J. M., Tapscott, S. J., Ghosh, A. Regulation of thalamocortical patterning and synaptic maturation by NeuroD2. Neuron 49: 683-695, 2006. 2. Lee, J. E., Hollenberg, S. M., Snider, L., Turner, D. L., Lipnick, N., Weintraub, H. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science 268: 836-844, 1995. 3. McCormick, M. B., Tamimi, R. M., Snider, L., Asakura, A., Bergstrom, D., Tapscott, S. J. neuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family. Molec. Cell. Biol. 16: 5792-5800, 1996.

Uniprot ID: Q15784

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 50 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 4761

Protein Name: Neurogenic differentiation factor 2

Gene Full Name: neuronal differentiation 2

Synonyms: bHLHa1; NDR2; NDRF; neuroD related factor; NeuroD2; neurogenic differentiation 2