Anti-NECAB2 Antibody Picoband®

SKU: A13886-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: NECAB2

Specificity:

Background: N-terminal EF-hand calcium-binding protein 2 is a protein that in humans is encoded by the NECAB2 gene. The protein encoded by this gene is a neuronal calcium-binding protein that binds to and modulates the function of at least two receptors, adenosine A(2A) receptor and metabotropic glutamate receptor type 5.

Immunogen: E.coli-derived human NECAB2 recombinant protein (Position: M1-E337).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Bernier, G., Vukovich, W., Neidhardt, L., Herrmann, B. G., Gruss, P. Isolation and characterization of a downstream target of Pax6 in the mammalian retinal primordium. Development 128: 3987-3994, 2001. 2. Canela, L., Lujan, R., Lluis, C., Burgueno, J., Mallol, J., Canela, E. I., Franco, R., Ciruela, F. The neuronal Ca(2+)-binding protein 2 (NECAB2) interacts with the adenosine A(2A) receptor and modulates the cell surface expression and function of the receptor. Molec. Cell Neurosci. 36: 1-12, 2007. 3. Zhang, M.-D., Barde, S., Szordorai, E., Josephson, A., Mitsios, N., Watanabe, M., Attems, J., Lubec, G., Kovacs, G. G., Uhlen, M., Mulder, J., Harkany, T., Hokfelt, T. Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord. Brain Struct. Funct. 221: 3803-3823, 2016. Note: Erratum: Brain Struct. Funct. 221: 3843, 2016.

Uniprot ID: Q7Z6G3

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 43 kDa

Calculated Molecular Weight: 64099 MW

Gene ID: 54550

Protein Name: N-terminal EF-hand calcium-binding protein 2

Gene Full Name: N-terminal EF-hand calcium binding protein 2

Synonyms: EFCBP2; NECAB2; Stip 2