Anti-MTR Antibody Picoband®

SKU: A01140-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: ELISA,Flow Cytometry,IHC,WB

Application Details: Western blot, 0.25-0.5μg/ml, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5μg/ml, -

Gene Name: MTR

Specificity: No cross reactivity with other proteins.

Background: Methionine synthase also known as MS, MeSe, MetH is responsible for the regeneration of methionine from homocysteine. In humans it is encoded by the MTR gene (5-methyltetrahydrofolate-homocysteine methyltransferase). It is mapped to 1q43. This gene encodes the 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Immunogen: E.coli-derived human MTR recombinant protein (Position: V880-D1095).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1.MTR 5-methyltetrahydrofolate-homocysteine methyltransferase (Homo sapiens). Entrez. 19 May 2009. Retrieved 24 May 2009. 2. Li YN, Gulati S, Baker PJ, Brody LC, Banerjee R, Kruger WD (December 1996). Cloning, mapping and RNA analysis of the human methionine synthase gene. Human Molecular Genetics. 5 (12): 1851–8. 3. Banerjee RV, Matthews RG (March 1990). Cobalamin-dependent methionine synthase. FASEB Journal. 4 (5): 1450–9.

Uniprot ID: Q99707

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate: This is the unconjugated antibody. It is also available with 10 conjugation options, including Biotin, Cy3, Fluoro488, Fluoro550, Fluoro594, FITC, HRP, APC, PE, and Fluoro647. A carrier-free (BSA-free) version is also available. Additional charges may apply for some options. Please contact us for a quote

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 140 kDa

Calculated Molecular Weight: 47643 MW

Gene ID: 4548

Protein Name: Methionine synthase

Gene Full Name: 5-methyltetrahydrofolate-homocysteine methyltransferase

Synonyms: cblG; Methionine synthase; MS; MTR