Anti-MOCS1 Antibody Picoband®

SKU: A07628-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: MOCS1

Specificity:

Background: Molybdenum cofactor biosynthesis protein 1 is a protein that in humans and other animals, fungi, and cellular slime molds, is encoded by the MOCS1 gene. Molybdenum cofactor biosynthesis is a conserved pathway leading to the biological activation of molybdenum. The protein encoded by this gene is involved in this pathway. This gene was originally thought to produce a bicistronic mRNA with the potential to produce two proteins (MOCS1A and MOCS1B) from adjacent open reading frames. However, only the first open reading frame (MOCS1A) has been found to encode a protein from the putative bicistronic mRNA, whereas additional splice variants are likely to produce a fusion between the two open reading frames. This gene is defective in patients with molybdenum cofactor deficiency, type A. A related pseudogene has been identified on chromosome 16.

Immunogen: E.coli-derived human MOCS1 recombinant protein (Position: E52-R584). Human MOCS1 shares 86.3% amino acid (aa) sequence identity with mouse MOCS1.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Reiss, J., Christensen, E., Dorche, C. Molybdenum cofactor deficiency: first prenatal genetic analysis. Prenatal Diag. 19: 386-388, 1999. 2. Reiss, J., Christensen, E., Kurlemann, G., Zabot, M.-T., Dorche, C. Genomic structure and mutational spectrum of the bicistronic MOCS1 gene defective in molybdenum cofactor deficiency type A. Hum. Genet. 103: 639-644, 1998. 3. Reiss, J., Cohen, N., Dorche, C., Mandel, H., Mendel, R. R., Stallmeyer, B., Zabot, M.-T., Dierks, T. Mutations in a polycistronic nuclear gene associated with molybdenum cofactor deficiency. Nature Genet. 20: 51-53, 1998.

Uniprot ID: Q9NZB8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 72 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 4337

Protein Name: Molybdenum cofactor biosynthesis protein 1

Gene Full Name: molybdenum cofactor synthesis 1

Synonyms: MOCS1; MIG11; MOCOD; MOCS1A; MOCS1B