Anti-Mcm7 Antibody (Monoclonal, DCS-141)

SKU: MA1058

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human

Applications: ICC,WB

Application Details: Immunocytochemistry , 1μg/ml, Human, -
Western blot, 0.5-1μg/ml, Human

Gene Name: MCM7

Specificity: No cross reactivity with other proteins.

Background: Initiation of DNA replication is a complex process involving the concerted action of many proteins. The chromosome 7-linked gene referred to by Nakatsuru et al. as MCM2 has been designated MCM7. The MCM2-7 complex is comprised of 6 subunits, MCM2 through MCM7, and is a ring-shaped heterohexameric ATPase involved in DNA replication. MCM7 is located in 7q21.3-q22.1.

Immunogen: Recombinant human Mcm7.

Clonality: Monoclonal

Contents: Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3. *This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Ascites

Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Reference: 1. Nakatsuru, S.; Sudo, K.; Nakamura, Y. : Isolation and mapping of a human gene (MCM2) encoding a product homologous to yeast proteins involved in DNA replication. Cytogenet. Cell Genet. 68: 226-230, 1995. 2. Pacek, M.; Tutter, A. V.; Kubota, Y.; Takisawa, H.; Walter, J. C. : Localization of MCM2-7, Cdc45, and GINS to the site of DNA unwinding during eukaryotic DNA replication. Molec. Cell 21: 581-587, 2006.

Uniprot ID: Q6AYN8

Host: Mouse

Concentration: Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Mouse IgG1

Phospho_site:

Clone Number: Clone: DCS-141

Observed Molecular Weight: 42 kDa

Calculated Molecular Weight: 81063 MW

Gene ID: Human(4176), Mouse(17220), Rat(288532)

Protein Name: DNA replication licensing factor MCM7

Gene Full Name: minichromosome maintenance complex component 7

Synonyms: CDC47; MCM2; P1.1-MCM3; P85MCM; P1CDC47; PNAS146; CDC47, S. CEREVISIAE, HOMOLOG OF; MCM7 minichromosome maintenance deficient 7(S. cerevisiae); minichromosome maintenance deficient(S. cerevisiae) 7; MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 7