Anti-MBNL3 Antibody Picoband®

SKU: A08298

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: MBNL3

Specificity:

Background: Muscleblind-like protein 3 is a protein that in humans is encoded by the MBNL3 gene. This gene encodes a member of the muscleblind-like family of proteins. The encoded protein may function in regulation of alternative splicing and may play a role in the pathophysiology of myotonic dystrophy. Alternatively spliced transcript variants have been described.

Immunogen: E.coli-derived human MBNL3 recombinant protein (Position: L106-C312).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Fardaei, M., Rogers, M. T., Thorpe, H. M., Larkin, K., Hamshere, M. G., Harper, P. S., Brook, J. D. Three proteins, MBNL, MBLL and MBXL, co-localize in vivo with nuclear foci of expanded-repeat transcripts in DM1 and DM2 cells. Hum. Molec. Genet. 11: 805-814, 2002. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/11/2012. 3. Ho, T. H., Charlet-B, N., Poulos, M. G., Singh, G., Swanson, M. S., Cooper, T. A. Muscleblind proteins regulate alternative splicing. EMBO J. 23: 3103-3112, 2004.

Uniprot ID: Q9NUK0

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 27 kDa

Calculated Molecular Weight:

Gene ID: 55796

Protein Name: Muscleblind-like protein 3

Gene Full Name: muscleblind like splicing regulator 3

Synonyms: MBNL3; CHCR; MBLX39; MBXL; Muscleblind-like protein 3; Cys3His CCG1-required protein; Muscleblind-like X-linked protein; Protein HCHCR