Anti-LRRC40 Antibody Picoband®

SKU: A16326-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC/IF,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: LRRC40

Specificity:

Background: Leucine rich repeat containing 40 (LRRC40) is a protein that in humans is encoded by the LRRC40 gene. The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic α/β horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC40 (leucine rich repeat containing 40) is a 602 amino acid protein that contains 20 LRR (leucine-rich) repeats.

Immunogen: E.coli-derived human LRRC40 recombinant protein (Position: R21-D598). Human LRRC40 shares 84.1% amino acid (aa) sequence identity with mouse LRRC40.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Pijuan, J. , Juan Darío Ortigoza‐Escobar, Ortiz, J. , Adrián Alcalá, María José Calvo, & Cubells, M. , et al. (2021). Plxna2 and lrrc40 as candidate genes in autism spectrum disorder. Autism Research. 2. Liu, H. , Cui, J. , Zhang, Y. , Niu, M. , Xue, X. , & Yin, H. , et al. (2019). Mass spectrometry‐based proteomic analysis of fscn1‐interacting proteins in laryngeal squamous cell carcinoma cells. IUBMB Life, 71(11). 3. Wang, Y. , Du, S. , Zhu, C. , Wang, C. , & Cai, Q. . (2020). Stub1 is targeted by the sumo-interacting motif of ebna1 to maintain epstein-barr virus latency. PLoS Pathogens, 16(3), e1008447.

Uniprot ID: Q9H9A6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 68 kDa

Calculated Molecular Weight:

Gene ID: 68 kDa

Protein Name: Leucine-rich repeat-containing protein 40

Gene Full Name: leucine rich repeat containing 40

Synonyms: LRRC40; Leucine-rich repeat-containing protein 40