Anti-Kv1.1 potassium channel/KCNA1 Antibody Picoband®

SKU: PA2296

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB

Application Details: Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat

Gene Name: KCNA1

Specificity: No cross reactivity with other proteins.

Background: Potassium voltage-gated channel subfamily A member 1, also known as Kv1.1, is a shaker related voltage-gated potassium channel that in humans is encoded by the KCNA1 gene. It is mapped to 12p13.32. The protein functions as a potassium selective channel through which the potassium ion may pass through in consensus with the electrochemical gradient. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kv1.1 potassium channel, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids .

Clonality: Polyclonal

Contents: Each vial contains antibody formulated with stabilizing components, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
*This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Albrecht B, Weber K, Pongs O (1995). Characterization of a voltage-activated K-channel gene cluster on human chromosome 12p13. Recept. Channels 3 (3): 213–20. 2. Curran ME, Landes GM, Keating MT (1992). Molecular cloning, characterization, and genomic localization of a human potassium channel gene. Genomics 12 (4): 729–37. 3. Entrez Gene: KCNA1 potassium voltage-gated channel

Uniprot ID: Q09470

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 56 kDa

Calculated Molecular Weight: 56466 MW

Gene ID: 3736

Protein Name: Potassium voltage-gated channel subfamily A member 1

Gene Full Name: potassium voltage-gated channel subfamily A member 1

Synonyms: AEMK; EA1; HBK1; HUK1; KCNA1; KV1.1; MBK1; MK1; RBK1