Anti-KLF15 Antibody Picoband®

SKU: A03661-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: KLF15

Specificity:

Background: Kruppel-like factor 15 is a protein that in humans is encoded by the KLF15 gene in the Kruppel-like factor family. KLF15, a kidney-enriched Krüppel-like zinc finger-containing transcription factors, is a transcriptonal activator that binds the CLCNKA promoter. The nuclear protein KLF15, is expressed primarily in liver, heart, skeletal muscle and kidney tissues but is not detected in lymphoid tissues or bone marrow. It is an important regulator of GLUT4 in both adipose and muscle tissues.Although the calculated molecular mass of KLF15 is 44 kDa, the apparent molecular mass on SDS–PAGE is 65 kDa due to the post-translational modifications.

Immunogen: E.coli-derived human KLF15 recombinant protein (Position: M1-C323).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Dmitriev, P., Petrov, A., Ansseau, E., Stankevicins, L., Charron, S., Kim, E., Bos, T. J., Robert, T., Turki, A., Coppee, F., Belayew, A., Lazar, V., Carnac, G., Laoudj, D., Lipinski, M., Vassetzky, Y. S. The Kruppel-like factor 15 as a molecular link between myogenic factors and a chromosome 4q transcriptional enhancer implicated in facioscapulohumeral dystrophy. J. Biol. Chem. 286: 44620-44631, 2011. 2. Fisch, S., Gray, S., Heymans, S., Haldar, S. M., Wang, B., Pfister, O., Cui, L., Kumar, A., Lin, Z., Sen-Banerjee, S., Das, H., Petersen, C. A., Mende, U., Burleigh, B. A., Zhu, Y., Pinto, Y. M., Liao, R., Jain, M. K. Kruppel-like factor 15 is a regulator of cardiomyocyte hypertrophy. Proc. Nat. Acad. Sci. 104: 7074-7079, 2007. Note: Erratum: Proc. Nat. Acad. Sci. 104: 13851 only, 2007. 3. Jeyaraj, D., Haldar, S. M., Wan, X., McCauley, M. D., Ripperger, J. A., Hu, K., Lu, Y., Eapen, B. L., Sharma, N., Ficker, E., Cutler, M. J., Gulick, J., and 9 others. Circadian rhythms govern cardiac repolarization and arrhythmogenesis. Nature 483: 96-99, 2012.

Uniprot ID: Q9UIH9

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 44 kDa

Calculated Molecular Weight: 28461 MW

Gene ID: 28999

Protein Name: Krueppel-like factor 15

Gene Full Name: KLF transcription factor 15

Synonyms: KLF15; KKLF; Krueppel-like factor 15; Kidney-enriched krueppel-like factor