Anti-ITPKC Antibody Picoband®

SKU: A07845-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: ELISA,Flow Cytometry,WB

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ITPKC

Specificity:

Background: This gene encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.

Immunogen: E.coli-derived human ITPKC recombinant protein (Position: D292-E607). Human ITPKC shares 88.1% and 88% amino acid (aa) sequence identity with mouse and rat ITPKC, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Chi, H., Huang, F.-Y., Chen, M.-R., Chiu, N.-C., Lee, H.-C., Lin, S.-P., Chen, W.-F., Lin, C.-L., Chan, H.-W., Liu, H.-F., Huang, L.-M., Lee, Y.-J. ITPKC gene SNP rs28493229 and Kawasaki disease in Taiwanese children. Hum. Molec. Genet. 19: 1147-1151, 2010. 2. Dewaste, V., Pouillon, V., Moreau, C., Shears, S., Takazawa, K., Erneux, C. Cloning and expression of a cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase C. Biochem. J. 352: 343-351, 2000. 3. Hamosh, A. Personal Communication. Baltimore, Md. 5/6/2020.

Uniprot ID: Q96DU7

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity:

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 100 kDa

Calculated Molecular Weight: 75 kDa

Gene ID: 80271

Protein Name: Inositol-trisphosphate 3-kinase C

Gene Full Name: inositol-trisphosphate 3-kinase C

Synonyms: ITPKC; IP3KC; Inositol-trisphosphate 3-kinase C; EC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase C; IP3 3-kinase C; IP3K C; InsP 3-kinase C