Anti-IMPI/IGF2BP1 Antibody Picoband®

SKU: A02007-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: ELISA,Flow Cytometry,WB

Application Details: Western blot, 0.1-0.25 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: IGF2BP1

Specificity:

Background: Insulin-like growth factor 2 mRNA-binding protein 1 is a protein that in humans is encoded by the IGF2BP1 gene. This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene.

Immunogen: E.coli-derived human IMPI/IGF2BP1 recombinant protein (Position: N8-Q562).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Doyle, G. A., Bourdeau-Heller, J. M., Coulthard, S., Meisner, L. F., Ross, J. Amplification in human breast cancer of a gene encoding a c-myc mRNA-binding protein. Cancer Res. 60: 2756-2759, 2000. 2. Hosono, Y., Niknafs, Y. S., Prensner, J. R., Iyer, M. K., Dhanasekaran, S. M., Mehra, R., Pitchiaya, S., Tien, J., Escara-Wilke, J., Poliakov, A., Chu, S.-C., Saleh, S., and 13 others. Oncogenic role of THOR, a conserved cancer/testis long non-coding RNA. Cell 171: 1559-1572, 2017. 3. Huttelmaier, S., Zenklusen, D., Lederer, M., Dictenberg, J., Lorenz, M., Meng, X., Bassell, G. J., Condeelis, J., Singer, R. H. Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature 438: 512-515, 2005.

Uniprot ID: Q9NZI8

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 63 kDa

Calculated Molecular Weight: 62616 MW

Gene ID: 10642

Protein Name: Insulin-like growth factor 2 mRNA-binding protein 1

Gene Full Name: insulin like growth factor 2 mRNA binding protein 1

Synonyms: CRD BP; CRDBP; IGF II mRNA binding protein 1; IGF2 mRNA binding protein 1; IGF2BP1; IMP 1; IMP1; VICKZ family member 1; VICKZ1; ZBP 1; ZBP1; Zip code binding protein 1; Zipcode binding protein 1