Anti-Human Siglec-3/CD33 Reference Antibody (Lintuzumab, RUO)

SKU: HB185026

Size:100ug

Description:Lintuzumab is a humanized monoclonal antibody, HuM195, that targets the cell surface antigen CD33 that is expressed on the vast majority of acute myeloid leukemia (AML) cells. [225Ac]Ac-lintuzumab clinical trials were discussed in detail in reference. Lintuzumab is under investigation in clinical trial NCT00016159 (Chemotherapy Plus Monoclonal Antibody in Treating Patients With Acute Promyelocytic Leukemia).

Host species:Humanized

Tested applications:

Species reactivity:Human

Form:Liquid

Storage buffer:0.01M PBS, pH 7.4.

Purity:>95% purity as determined by SDS-PAGE.

Clonality:Monoclonal

Isotype:IgG1-kappa

Applications:ELISA, Bioactivity: FACS, Functional assay, Research in vivo

Target:Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, CD33, gp67, SIGLEC3

Purification:Protein A/G purified from cell culture supernatant.

Endotoxin level:Please contact us for this information.

Expression system:Mammalian Cells

Accession:P20138

Stability and Storage:Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Reconstitution:

Background:

Alternative Names:225Ac-lintuzumab, HuM195, SGN-33, SMARTM195, HuM195, 166089-32-3

Clone ID:

Species:

Note:For research use only. Not suitable for clinical or therapeutic use.