Anti-Filensin Bfsp1 Antibody (Monoclonal, FIL-7B10)

SKU: MA1041

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Bovine,Human

Applications: IHC,WB

Application Details: Immunohistochemistry (Frozen Section), 2-4μg/ml, Human, bovine, -
Western blot, 1-2μg/ml, Human, bovine

Gene Name: BFSP1

Specificity: No cross reactivity with other proteins.

Background: Filensin, also known as beaded filament structure protein 1, have two major component BFSP1 and BESP2. Filensin gene is mapped at 20p12.1-p11.23. The sequence of the predicted 665-amino acid human protein is 62% and 50% identical to those of bovine and chicken filensin, respectively. However, it has less than 26% identity to other members of the intermediate filament (IF) family.

Immunogen: Human and bovine lens filament enriched fraction (plasma membrane-cytoskeleton complex).

Clonality: Monoclonal

Contents: Mouse IgG in stabilizing components, 1.2% sodium acetate and 0.01mg NaN3. *This antibody is supplied in a stabilized formulation.
Compatibility with conjugation reactions depends on the chemistry of the conjugation method used.
For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Purification: Ascites

Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Reference: 1. Rendtorff, N. D.; Hansen, C.; Silahtaroglu, A.; Henriksen, K. F.; Tommerup, N. : Isolation of the human beaded-filament structural protein 1 gene (BFSP1) and assignment to chromosome 20p11.23-p12.1. Genomics 53: 114-116, 1998. 2. Hess, J. F.; Casselman, J. T.; FitzGerald, P. G. : Chromosomal locations of the genes for the beaded filament proteins CP 115 and CP 47. Curr. Eye Res. 14: 11-18, 1995.

Uniprot ID: Q02435

Host: Mouse

Concentration: Adding 1 ml of PBS buffer will yield a concentration of 100 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Mouse IgG1

Phospho_site:

Clone Number: Clone: FIL-7B10

Observed Molecular Weight: 426 kDa

Calculated Molecular Weight: 68038 MW

Gene ID: Human(631), Mouse(12075), Rat(25394)

Protein Name: Filensin

Gene Full Name: beaded filament structural protein 1

Synonyms: CP115; CP94; CP115; LIFL-H; LIFL-H CYTOSKELETAL PROTEIN, 115-KD; Beaded filament structural protein 1; Lens fiber cell beaded-filament structural protein CP 115; Lens intermediate filament-like heavy