Anti-ELP2 Antibody Picoband®

SKU: A07823-2

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC/IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: ELP2

Specificity:

Background: The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.

Immunogen: E.coli-derived human ELP2 recombinant protein (Position: D84-L826). Human ELP2 shares 77.9% and 79.8% amino acid (aa) sequence identity with mouse and rat ELP2, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Cohen, J. S., Srivastava, S., Farwell, K. D., Lu, H.-M., Zeng, W., Lu, H., Chao, E. C., Fatemi, A. ELP2 is a novel gene implicated in neurodevelopmental disabilities. Am. J. Med. Genet. 167A: 1391-1395, 2015. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 10/14/2014. 3. Hawkes, N. A., Otero, G., Winkler, G. S., Marshall, N., Dahmus, M. E., Krappmann, D., Scheidereit, C., Thomas, C. L., Schiavo, G., Erdjument-Bromage, H., Tempst, P., Svejstrup, J. Q. Purification and characterization of the human elongator complex. J. Biol. Chem. 277: 3047-3052, 2002.

Uniprot ID: Q6IA86

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 93 kDa

Calculated Molecular Weight: 93 kDa

Gene ID: 55250

Protein Name: Elongator complex protein 2

Gene Full Name: elongator acetyltransferase complex subunit 2

Synonyms: Elongator complex protein 2; ELP2; SHINC 2; STAT3 interacting protein 1; STATIP1; StIP; StIP1