Anti-EIF4H Antibody Picoband®

SKU: A05539-1

Size: 100 μg

Storage: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Monkey

Applications: WB,ICC/IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Monkey
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml

Gene Name: EIF4H

Specificity:

Background: This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.

Immunogen: E.coli-derived human EIF4H recombinant protein (Position: M1-E248). Human EIF4Hshares 98.8% and 98% amino acid (aa) sequence identity with mouse and rat EIF4H, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Osborne, L. R., Martindale, D., Scherer, S. W., Shi, X.-M., Huizenga, J., Heng, H. H. Q., Costa, T., Pober, B., Lew, L., Brinkman, J., Rommens, J., Koop, B., Tsui, L.-C. Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients. Genomics 36: 328-336, 1996. 2. Richter-Cook, N. J., Dever, T. E., Hensold, J. O., Merrick, W. C. Purification and characterization of a new eukaryotic protein translation factor: eukaryotic initiation factor 4H. J. Biol. Chem. 273: 7579-7587, 1998.

Uniprot ID: Q15056

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 25 kDa

Calculated Molecular Weight: 25 kDa

Gene ID: 7458

Protein Name: Eukaryotic translation initiation factor 4H

Gene Full Name: eukaryotic translation initiation factor 4H

Synonyms: eIF 4H; EIF4H; KIAA0038; WBSCR1; WSCR1