Anti-BCMA/Tnfrsf17 Antibody Picoband®

SKU: A01014-4

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Mouse,Rat

Applications: Flow Cytometry,IHC,WB

Application Details: Western blot, 0.25-0.5μg/ml, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse, Rat
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Mouse

Gene Name: Tnfrsf17

Specificity:

Background: B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse BCMA/Tnfrsf17, which shares 78.9% and 95% amino acid (aa) sequence identity with human and rat BCMA/Tnfrsf17, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Entrez Gene: TNFRSF17 tumor necrosis factor receptor superfamily, member 17. 2. Laabi Y, Gras MP, Brouet JC, Berger R, Larsen CJ, Tsapis A (Apr 1994). The BCMA gene, preferentially expressed during B lymphoid maturation, is biionally transcribed. Nucleic Acids Research. 22 (7): 1147–54.

Uniprot ID: O88472

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 30 kDa

Calculated Molecular Weight:

Gene ID: 21935

Protein Name: Tumor necrosis factor receptor superfamily member 17

Gene Full Name: tumor necrosis factor receptor superfamily, member 17

Synonyms: TNF receptor superfamily member 17; BCM; BCMA; CD269; TNFRSF13A; Tnfrsf17