Anti-BAL/SLC27A5 Antibody Picoband®

SKU: A09287-2

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Rat

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SLC27A5

Specificity:

Background: Bile acyl-CoA synthetase is an enzyme that in humans is encoded by the SLC27A5 gene. The protein encoded by this gene is an isozyme of very long-chain acyl-CoA synthetase (VLCS). It is capable of activating very long-chain fatty-acids containing 24- and 26-carbons. It is expressed in liver and associated with endoplasmic reticulum but not with peroxisomes. Its primary role is in fatty acid elongation or complex lipid synthesis rather than in degradation. This gene has a mouse ortholog.

Immunogen: E.coli-derived human BAL/SLC27A5 recombinant protein (Position: I204-L690).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Berger, J., Truppe, C., Neumann, H., Forss-Petter, S. A novel relative of the very-long-chain acyl-CoA synthetase and fatty acid transporter protein genes with a distinct expression pattern. Biochem. Biophys. Res. Commun. 247: 255-260, 1998. 2. Chong, C. P. K., Mills, P. B., McClean, P., Gissen, P., Bruce, C., Stahlschmidt, J., Knisely, A. S., Clayton, P. T. Bile acid-CoA ligase deficiency--a new inborn error of bile acid metabolism. J. Inherit. Metab. Dis. 35: 521-532, 2012. 3. Doege, H., Baillie, R. A., Ortegon, A. M., Tsang, B., Wu, Q., Punreddy, S., Hirsch, D., Watson, N., Gimeno, R. E., Stahl, A. Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic liver homeostasis. Gastroenterology 130: 1245-1258, 2006.

Uniprot ID: Q9Y2P5

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 75 kDa

Calculated Molecular Weight: 94661 MW

Gene ID: 10998

Protein Name: Long-chain fatty acid transport protein 5

Gene Full Name: solute carrier family 27 member 5

Synonyms: SLC27A5; ACSB; ACSVL6; FACVL3; FATP5; Bile acyl-CoA synthetase; BACS; Bile acid-CoA ligase; BA-CoA ligase; BAL; Cholate--CoA ligase; Fatty acid transport protein 5; FATP-5; Fatty-acid-coenzyme A ligase; very long-chain 3; Solute carrier family 27 member 5; Very long-chain acyl-CoA synthetase homolog 2; VLCS-H2; VLCSH2; Very long-chain acyl-CoA synthetase-related protein; VLACS-related; VLACSR