Anti-alpha 1 Fetoprotein/AFP Antibody Picoband®

SKU: A00522-3

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: AFP

Specificity:

Background: AFP, also called Alpha-fetoprotein; alpha-fetoprotein, is a protein that in humans is encoded by the AFP gene. It is mapped to 4q13.3. The level of AFP in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. In rodents AFP binds estradiol to prevent the transport of this hormone across the placenta to the fetus. The main function of this is to prevent the virilization of female fetuses. Moreover, it has an important role as a diagnostic marker, especially in certain tumors and liver diseases of childhood. AFP is also used to test the potential usefulness of plasma alpha fetoprotein determination as a diagnostic marker in biliary atresia, hepatitis, and yolk sac derived tumours.

Immunogen: E.coli-derived human alpha 1 Fetoprotein/AFP recombinant protein (Position: R19-L258).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Carter CS (2002). Neuroendocrinology of sexual behavior in the female. In Becker JB. Behavioral Endocrinology. Cambridge, Mass: MIT Press. pp.88-89. ISBN 0-262-52321-3 2. Bader D, Riskin A, Vafsi O, Tamir A, Peskin B, Israel N, Merksamer R, Dar H, David M (November 2004). Alpha-fetoprotein in the early neonatal period--a large study and review of the literature. Clin. Chim. Acta 349 (1-2): 15–23. 3. Blair JI, Carachi R, Gupta R, Sim FG, McAllister EJ, Weston R (April 1987). Plasma alpha fetoprotein reference ranges in infancy: effect of prematurity. Arch. Dis. Child. 62 (4): 362–9.

Uniprot ID: P02771

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 69 kDa

Calculated Molecular Weight:

Gene ID: 174

Protein Name: Alpha-fetoprotein

Gene Full Name: alpha fetoprotein

Synonyms: AFP; Alpha 1 fetoprotein; Alpha fetoglobulin; alpha fetoprotein; FETA; HPAFP