Anti-Acid phosphatase/ACP1 Antibody Picoband®

SKU: A02167-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ACP1

Specificity:

Background: Low molecular weight phosphotyrosine protein phosphatase is an enzyme that in humans is encoded by the ACP1 gene. The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.

Immunogen: E.coli-derived human Acid phosphatase/ACP1 recombinant protein (Position: M1-H158).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Arnaud, J., Vavrusa, B., Sevin, J., Constans, J. Human red-cell acid phosphatase (ACP1): a new mutant (ACP1*KUK) detected by isoelectric focusing, kinetics of thermostability and substrate activity. Hum. Hered. 39: 288-293, 1989. 2. Arnaud, J., Vavrusa, B., Wiederanders, G., Constans, J. Human red-cell acid phosphatase (ACP1): kinetic and thermodynamic characterization of the KUK variant. Hum. Hered. 42: 140-142, 1992. 3. Beemer, F. A., van der Heiden, C., Van Hemel, J. O., Jansen, M. Letter to the editors. (Letter) Clin. Genet. 24: 151, 1983.

Uniprot ID: P24666

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 17 kDa

Calculated Molecular Weight: 63692 MW

Gene ID: 52

Protein Name: Low molecular weight phosphotyrosine protein phosphatase

Gene Full Name: acid phosphatase 1

Synonyms: acid phosphatase 1; soluble; ACP1; Adipocyte acid phosphatase; HAAP; LMW PTP; LMW PTPase; Red cell acid phosphatase 1