Annexin A1 Polyclonal Antibody

SKU: AN007180L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:Annexin A1

Target Synonym:ANX;Annexin I (lipocortin I);AnnexinA1;AnnexinI;ANX 1;ANX A1;ANXA 1;ANXA1 protein;CalpactinII;Chromobindin9;HGNC:533;Lipocortin 1;lipocortin I;ANX1;LPC1;Annexin I;Annexin-1;Calpactin II;Calpactin-2;Chromobindin-9;Lipocortin I;Phospholipase A2 inhibitory protein;p35;Lipocortin1;LipocortinI;LPC 1;LPC;ANXA;Annexin A;ANXA1;ANX1;LPC1;Annexin 1;Calpactin 2;Chromobindin 9;Annexin-1;Chromobindin-9;p35;Calpactin-2;Annexin A1;Annexin I;Calpactin II;Lipocortin I;Phospholipase A2 Inhibitory Protein

Research Areas:Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P04083

Accession:

Background:Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells. Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells.Has no effect on unstimulated T cells. Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton.Has high affinity for Ca2+ and can bind up to eight Ca2+ ions. Displays Ca2+-dependent binding to phospholipid membranes. Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca2+-dependent interaction between phagosomes and the actin cytoskeleton.

Concentration:1 mg/mL

Immunogen:Recombinant Human Annexin A1 protein expressed by E.coli

Buffer:PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4

Purification method:Antigen Affinity Purification

Dilution:WB 1:5000-1:10000

Calculated MW:38 kDa

ObservedMW:35 kDa