Androgen receptor Monoclonal Antibody

SKU: BT-MCA4634

Size:100μL

Background:The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype.

Research_area:Others

Target_protein:Androgen receptor

applications:WB, IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:2H8

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:Androgen receptor

Immunogen:Purified recombinant fragment of human AR expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):110kDa

UniProt accession:P10275

Synonyms:NR3C4, KD, AIS, SMAX1, HUMARA, AR

GeneID:367