ALX4 Antibody - Cat. #: CSB-PA992612

SKU: CSB-PA992612

Size :50ul

Clone Number:

Aliases:Alx4 antibody; ALX4_HUMAN antibody; Aristaless like homeobox 4 antibody; CRS5 antibody; FND2 antibody; FPP antibody; homeobox protein aristaless like 4 antibody; Homeobox protein aristaless-like 4 antibody; homeodomain transcription factor ALX4 antibody; KIAA1788 antibody; PFM1 antibody; PFM2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H161

Immunogen:Synthetic peptide of Human ALX4

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100

Background:This gene encodes a paired-like homeodomain transcription factor expressed in the mesenchyme of developing bones, limbs, hair, teeth, and mammary tissue. Mutations in this gene cause parietal foramina 2 (PFM2); an autosomal dominant disease characterized by deficient ossification of the parietal bones. Mutations in this gene also cause a form of frontonasal dysplasia with alopecia and hypogonadism; suggesting a role for this gene in craniofacial development, mesenchymal-epithelial communication, and hair follicle development. Deletion of a segment of chromosome 11 containing this gene, del(11)(p11p12), causes Potocki-Shaffer syndrome (PSS); a syndrome characterized by craniofacial anomalies, mental retardation, multiple exostoses, and genital abnormalities in males. In mouse, this gene has been shown to use dual translation initiation sites located 16 codons apart.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ALX4

Research Areas:Epigenetics and Nuclear Signaling