ALKBH2 Polyclonal Antibody

SKU: E-AB-10700

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:ALKBH2

Target Synonym:2OG Fe(II) oxy DC1;9530023G02;ABH 2;ABH2;alkB alkylation repair homolog 2;ALKB2;ALKBH2 alkB;ALKBH2;Alkylated DNA repair protein alkB homolog;Alkylated DNA repair protein alkB homolog 2;Alkylation repair homolog 2;Alpha ketoglutarate dependent dioxygenase alkB homolog 2;Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2;AU016977;DNA oxidative demethylase ALKBH2;EC 1.14.11.;FLJ99103;hABH2;mABH2;MGC90512;Oxy DC1

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q6NS38

Accession:

Background:The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.

Concentration:0.3 mg/mL

Immunogen:Recombinant protein of human ALKBH2

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:29kDa

ObservedMW: