Aldolase C antibody , Cat. # FNab00304

SKU: FNab00304

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:6F3

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Fructose-bisphosphate aldolase C(ALDOC) reversibly cleaves FBP and F1-P to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate and is strongly expressed in mammalian brain together with ALDOA and is alsopresent in the heart and spleen of some species(PMID:9363598). It is involed in glycolysis as an important enzyme. Phospholipase D2 and inositol 1,4,5-triphosphate interact with ALDOC in signal transduction. Meanwhile, the protein expression of ALDOC has been reported to be regulated in brain tumor, hepatomas, and lung cancer(PMID:21548097).

Immunogen:aldolase C, fructose-bisphosphate

Synonyms:ALDOC, Aldolase C, Brain type aldolase, Fructose bisphosphate aldolase C

Observed MW:39 kDa

Uniprot ID:P09972

Reactivity:Human

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:5000-1:50000; IHC: 1:50-1:500; IF: 1:20-1:200

Gene ID:230

Research Area:Metabolism