AK1C4 Polyclonal Antibody

SKU: BT-AP06132

Size:100μL

Background:This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.

Research_area:Cancer; Metabolism; Signal transduction

Target_protein:AKR1C4

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Aldo-keto reductase family 1 member C4

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P17516

Synonyms:Aldo-keto reductase family 1 member C4 ;EC 1.1.1.-;3-alpha-HSD1;3-alpha-hydroxysteroid dehydrogenase type I;EC 1.1.1.50;Chlordecone reductase;CDR;EC 1.1.1.225;Dihydrodiol dehydrogenase 4

GeneID:Human: 1109