AF/LE Purified Anti-Mouse/Human GAL3 Antibody[M3/38]

SKU: AN003440

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:GAL3

Target Synonym:MAC;Galactose-specific lectin;Galactoside-Binding Soluble;Galectin;Lectin L;GAL;CBP;LGALS3;CBP35;GAL3;GALBP;GALIG;L31;LGALS2;MAC2;Galactoside-Binding Soluble 3;Lectin;Galectin-3;Gal-3;L-31;35 kDa lectin;CBP 35;Galactose-specific lectin 3;IgE-binding protein;Laminin-binding protein;Lectin L-29;Mac-2 antigen;Carbohydrate binding protein 35;Carbohydrate-binding protein 35;galactose binding;galactoside binding soluble 3;Galactoside-binding protein;galectin 3;Galectin 3 internal gene;Galectin3;GBP;IgE binding protein;included;L 31;L 34;L-34 galactoside-binding lectin;Lectin;Galactoside-Binding Soluble 3;LEG3;MAC 2 antigen;Mac-2;Macrophage galactose-specific lectin;MGC105387;P35;soluble 3

Research Areas:Neuroscience;Cell Biology

Conjugation:None (AF/LE)

Host:Rat

Species reactivity:Mouse/Human

Application:FCM

Usage:

Isotype:Rat IgG2a, κ

Clonality:Monoclonal

Clone NO.:M3/38

UNIProt ID:P17931

Background:Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Mouse GAL3 protein

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:3958