AF/LE Purified Anti-Human CD80 Antibody[2D10]

SKU: GBS-F12320

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD80

Target Synonym:LAB;CTLA-4 counter-receptor B;T-lymphocyte activation antigen CD;B7;B7-1;B7.1;BB1;CD28LG;CD28LG1;LAB7;CD80;CD28LGB7-1 antigen;T-lymphocyte activation antigen CD80;Activation B7-1 antigen;CTLA-4 counter-receptor B7.1; B7-1; BB1;B lymphocyte activation antigen B7;B7-1 antigen;B7-1 antigen);CD28 antigen ligand 1;CD80 antigen;CD80 antigen (CD28 antigen ligand 1;CD80 molecule;Costimulatory factor CD80;costimulatory molecule variant IgV-CD80

Research Areas:Immunology;Stem Cells

Conjugation:None (AF/LE)

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:2D10

UNIProt ID:P33681

Background:B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD80 protein

Buffer:Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:941