Active Caspase 3 Mouse mAb

SKU: EM1188

Size: 100μL

Source:Mouse

Applications:WB, IHC

Reactivity:Human, Rat, Mouse

Dilution:WB 1:500-1,000 IHC 1:100-200

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):17kDa

Human_gene_id:836

Human_swiss_prot_no:P42574

Subcellular_location:Cytoplasm

Other_name:APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody

Background:Activation of caspase-3 requires proteolytic processing of its inactive zymogen into activated p17 and p12 fragments. Cleavage of caspase-3 requires aspartic acid at the P1 position.