ACSL3 Polyclonal Antibody

SKU: BT-AP14113

Size:100μL

Background:The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity| subcellular localization| and tissue distribution| all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters| and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain| and preferentially utilizes myristate| arachidonate| and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.

Research_area:Cardiovascular; Metabolism; Signal transduction

Target_protein:ACSL3

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Long-chain-fatty-acid--CoA ligase 3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O95573; Mouse: Q9CZW4; Rat: Q63151

Synonyms:Long-chain-fatty-acid--CoA ligase 3 ;EC 6.2.1.3;Long-chain acyl-CoA synthetase 3;LACS 3

GeneID:Human: 2181