AChE Polyclonal Antibody

SKU: BT-AP14090

Size:100μL

Background:Acetylcholinesterase hydrolyzes the neurotransmitter| acetylcholine at neuromuscular junctions and brain cholinergic synapses| and thus terminates signal transmission. It is also found on the red blood cell membranes| where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties| but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene| and the structural diversity in the gene products arises from alternative mRNA splicing| and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain| muscle and other tissues is the hydrophilic species| which forms disulfide-linked oligomers with collagenous| or lipid-containing structural subunits. The other| alternatively

Research_area:Cardiovascular; Neuroscience; Cancer; Immunology; Metabolism

Target_protein:ACHE

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Acetylcholinesterase

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):67796

UniProt accession:Human: P22303; Mouse: P21836; Rat: P37136

Synonyms:Acetylcholinesterase; ACHE; Acetylcholinesterase; AChE

GeneID:Human: 43; Mouse: 11423; Rat: 83817