ABCB4 Polyclonal Antibody

SKU: E-AB-53413

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:ABCB4

Target Synonym:ABC 21;ABC B4;ABC21;ABCB 4;Abcb4;ABCB4 protein;ATP binding cassette sub family B MDR/TAP member 4;ATP binding cassette sub family B member 4;ATP-binding cassette sub-family B member 4;GBD1;ICP3;MDR 3;MDR2;MDR2/3;MDR3;MDR3 P glycoprotein;MDR3 P gp;MDR3;Multidrug resistance protein 3;Multiple drug resistance 3;P glycoprotein 3 ;P-glycoprotein 3;PFIC 3;PFIC3;PGY 3;PGY3

Research Areas:Cancer;Metabolism;Signal transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P21439

Accession:

Background:The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.

Concentration:1.2 mg/mL

Immunogen:Synthetic peptide of human ABCB4

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:40-1:200

Calculated MW:

ObservedMW: