AASS rabbit pAb

SKU: ES1560

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human AASS. AA range:251-300

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):102kD

Human_gene_id:10157

Human_swiss_prot_no:Q9UDR5

Subcellular_location:Mitochondrion .

Other_name:AASS; Alpha-aminoadipic semialdehyde synthase; mitochondrial; LKR/SDH

Background:This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia. [provided by RefSeq, Jul 2008],