TRAF3 Antibody - Cat. #: CSB-PA940722

SKU: CSB-PA940722

Size :50ul

Clone Number:

Aliases:CAP 1 antibody; CAP-1 antibody; CAP1 antibody; CD40 associated protein 1 antibody; CD40 binding protein antibody; CD40 bp antibody; CD40 receptor associated factor 1 antibody; CD40 receptor-associated factor 1 antibody; CD40-binding protein antibody; CD40BP antibody; CRAF 1 antibody; CRAF1 antibody; IIAE5 antibody; LAP 1 antibody; LAP1 antibody; LMP1 associated protein antibody; LMP1-associated protein 1 antibody; MIPT3 antibody; TNF receptor associated factor 3 antibody; TNF receptor-associated factor 3 antibody; TRAF 3 antibody; Traf3 antibody; TRAF3_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13114

Immunogen:Synthetic peptide of Human TRAF3

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100

Background:The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TRAF3

Research Areas:Cancer;Immunology;Signal transduction