TGFBI Polyclonal Antibody

SKU: E-AB-52170

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: TGFBI

Target Synonym: >RGD containing collagen associated protein;AI181842;AI747162;Beta ig;Beta ig h3;Beta ig-h3;BGH3;Big h3;BIGH3;CDB1;CDG2;CDGG1;CSD;CSD1;CSD2;CSD3;EBMD;Kerato epithelin;Kerato-epithelin;LCD1;MGC150270;RGD CAP;RGD-CAP;RGD-containing collagen-associated protein;TGFBI;TGFBI transforming growth factor;beta induced;68kDa;Transforming growth factor beta induced protein ig h3;Transforming growth factor-beta-induced protein ig-h3

Research Areas: Cancer;Developmental Biology;Neuroscience;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q15582

Accession:

Background: TGFBI,also named as BIGH3,Kerato-epithelin and RGD-CAP,binds to type I,II,and IV collagens. TGFBI is an adhesion protein which may play an important role in cell-collagen interactions. In cartilage,it may be involved in endochondral bone formation. TGFBI is an extracellular matrix adaptor protein,it has been reported to be differentially expressed in transformed tissues. TGFBI is a predictive factor of the response to chemotherapy,and suggest the use of TGFBI-derived peptides as possible therapeutic adjuvants for the enhancement of responses to chemotherapy. Defects in TGFBI are the cause of epithelial basement membrane corneal dystrophy (EBMD). Defects in TGFBI are the cause of corneal dystrophy Groenouw type 1 (CDGG1). Defects in TGFBI are the cause of corneal dystrophy lattice type 1 (CDL1). Defects in TGFBI are a cause of corneal dystrophy Thiel-Behnke type (CDTB). Defects in TGFBI are the cause of Reis-Buecklers corneal dystrophy (CDRB). Defects in TGFBI are the cause of lattice corneal dystrophy type 3A (CDL3A). Defects in TGFBI are the cause of Avellino corneal dystrophy (ACD).

Concentration: 1.32 mg/mL

Immunogen: Fusion protein of human TGFBI

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW: 75 kDa

ObservedMW: Refer to figures