Recombinant Mouse Interleukin-36 gamma/IL-36 gamma/IL-1F9

SKU: PKSM041397

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Cytokines

Abbreviation: IL-36 gamma;IL-1F9

Target Synonym: Il1f;IL-1-related protein;Interleukin-1 homolog;IL-1F;IL-1H;IL-1RP;IL-1 epsilon;IL-1F9;IL-1H1;IL-1-related protein 2;IL-1RP2;Interleukin-1 homolog 1;Interleukin-36 gamma;Il1f9;Il36g;IL-17E

Research Areas:

Conjugation:

Target Species: Mouse

Expression Host: E.coli

Application:

Fusion tag: None

UNIProt ID: Q8R460

Accession: Q8R460

Background: Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in both neuronal and synovial tissue, whereas IL-36β and IL-36γ are expressed in both cutaneous and mucosal epithelial cells, including the respiratory tract. IL-36β and IL-36γ stimulate proliferation, maturation and/or cytokine expression by innate immune cells (such as keratinocytes and dendritic cells), and adaptive immune cells (neutrophils and T-cells) in both humans and mice. The activity of IL-36α is mediated by interleukin 1 receptor-like 2 (IL1RL2/IL1R-rp2), and is specifically inhibited by interleukin 1 family, member 5 (IL1F5/IL-1 delta). IL-36γ plays an important role in communicating the cell death to surrounding cells.

Concentration:

Activity: Not validated for activity

Sequence: Gly13-Ser164

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2μm filtered solution of 20mM Histidine-HCl, 10% Trehalose, 0.05% Tween 80, pH5.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 17.3 kDa

ObservedMW: 17 kDa