Phospho-EEF2K (Ser366) Polyclonal Antibody

SKU: E-AB-21142

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Acetyl/Phospho/Methyl Antibodies

Abbreviation: eEF2K (phospho Ser366)

Target Synonym: C86191;Calcium/calmodulin dependent eukaryotic elongation factor 2;Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase;Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase;Calmodulin dependent protein kinase III;cb365;EC 2.7.11.20;eEF 2 kinase;eEF 2K;eEF-2 kinase;eEF-2K;Eef2k;EEF2K protein;EF2K;Elongation factor 2 kinase;Eukaryotic elongation factor 2 kinase;fa04b08;HSU93850;kinase eEF2K;MGC45041;SMEF2K;wu:fa04b08;zgc:100973

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Rat

Application: WB;IHC-p

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: O00418

Accession:

Background: This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human eEF2K around the phosphorylation site of Ser366

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300

Calculated MW: 82kDa

ObservedMW: 105kDa