DKK3 Antibody - Cat. #: CSB-PA890660LA01HU

SKU: CSB-PA890660LA01HU

Size :50ug

Clone Number:

Aliases:Dickkopf 3 antibody; Dickkopf 3 homolog (Xenopus laevis) antibody; Dickkopf 3 homolog antibody; Dickkopf homolog 3 antibody; Dickkopf related protein 3 antibody; Dickkopf related protein 3 Precursor antibody; Dickkopf WNT signaling pathway inhibitor 3 antibody; Dickkopf; Xenopus; homolog of; 3 antibody; Dickkopf-3 antibody; Dickkopf-related protein 3 antibody; Dickkopf3 antibody; DKK 3 antibody; Dkk-3 antibody; DKK3 antibody; DKK3_HUMAN antibody; hDkk 3 antibody; hDkk-3 antibody; hDkk3 antibody; Regulated in glioma antibody; REIC antibody; RIG antibody; RIG-like 5-6 antibody; RIG-like 7-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UBP4

Immunogen:Recombinant Human Dickkopf-related protein 3 protein (22-350AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:DKK3

Research Areas:Signal transduction; Stem cells