YWHAB antibody , Cat. # FNab09575

SKU: FNab09575

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form(by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2. Negative regulator of signaling cascades that mediate activatation of MAP kinases via AKAP13.

Immunogen:tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide

Synonyms:14 3 3, 14 3 3 alpha, 14 3 3 protein beta/alpha, YWHAB

Observed MW:28 kDa

Uniprot ID:P31946

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:20-1:200

Gene ID:7529

Research Area:Neuroscience, Signal Transduction, Metabolism